The HPRT1 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to HPRT1. This antibody recognizes Human, Mouse, and Rat antigen. The HPRT1 Polyclonal Antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout